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Bio X Cell Antibody, TIM-1 (CD365), Clone 3D10, Rat IgG1, 1 MG

Supplier:  Bio X Cell BE0314R001MG

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This monoclonal antibody, clone 3D10, targets mouse T cell immunoglobulin and mucin domain 1 (TIM-1), also known as CD365. TIM-1, a type I cell-surface glycoprotein within the Ig superfamily, is predominantly expressed on TH2 cells and acts as a stimulatory molecule for T cell activation. It plays crucial roles in regulating immune responses to viral infections, allergic reactions, asthma, and transplant tolerance. This antibody has been shown to block TIM-1 in vivo and enhance atherosclerosis in mice studies.

  • Reacts with mouse TIM-1 (CD365)
  • Isotype: Rat IgG1,
  • Formulated in PBS, pH 7.0, without stabilizers or preservatives
  • Low endotoxin level (1EU/mg)
  • Purity greater than 95%
  • Sterility achieved by 0.2 m filtration
  • Suitable for in vivo and in vitro TIM-1 blockade

Catalog No. 50-190-4517


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