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Bio X Cell anti-mouse TL1A Monoclonal Antibody, 5G4.6, 1 MG
Supplier: Bio X Cell BE0323R001MG
The 5G4.6 monoclonal antibody targets the TNF family member TL1A (TNFSF15), which is expressed on activated T cells, dendritic cells, monocytes, and endothelial cells. This antibody blocks TL1A binding to DR3, reducing disease severity in mouse models of colitis by inhibiting effector T cell proliferation at inflammation sites.
- Clone: 5G4.6
- Reactivities: Mouse
- Isotype: Armenian hamster IgG
- Host: Armenian hamster
- Target: TL1A (TNFSF15)
- Purification: Protein A
- Formulation: PBS, pH 7.0
- Endotoxin: ≤1 EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage: Store at 4°C; do not freeze
- Applications: In vivo TL1A neutralization, Flow cytometry
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