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Bio X Cell InVivoMAb Antibody, anti-mouse TL1A (TNFSF15), Armenian Hamster IgG, 25 MG
Supplier: Bio X Cell BE0323R005MG
This 5G4.6 monoclonal antibody targets TL1A (TNFSF15), a TNF family member expressed on various immune cells and induced by pro-inflammatory stimuli. Its receptor, DR3 (TNFRSF25), found on T cells, NK cells, and NKT cells, mediates T cell proliferation at inflammation sites. Blocking TL1A-DR3 interactions has shown reduced pathology in animal models of autoimmune diseases.
- Isotype: Armenian hamster IgG
- Immunogen: Recombinant murine TL1A
- Applications: in vivo TL1A neutralization, flow cytometry
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: 1 EU/mg
- Purity: 95% by SDS-PAGE
- Sterility: 0.2 m filtration
- Molecular weight: 150 kDa
- Storage: 4C, do not freeze
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