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Bio X Cell Monoclonal Antibody, mouse TIM-3, B8.2C12, 1 MG
Supplier: Bio X Cell BE0275R001MG
The B8.2C12 monoclonal antibody targets mouse TIM-3 (T cell immunoglobulin and mucin domain-3), also known as CD366. It strongly binds to the BALB/c allele of TIM-3, with weaker reactivity to the C57Bl/6 allele. TIM-3 is a 60 kDa immune checkpoint receptor, crucial for inducing tolerance and investigated as a target for cancer immunotherapy.
- Designed for in vivo functional studies
- Immune checkpoint regulator, targeting TIM-3
- Purity of ≥95% determined by SDS-PAGE
- Endotoxin of ≤1EU/mg determined by LAL assay
- Sterile with 0.2 μm filtration
- Produced in an animal-free facility
- Recommended isotype control: InVivoMAb rat IgG1, anti-horseradish peroxidase
- Recommended dilution buffer: InVivoPure pH 7.0 Dilution Buffer
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