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Bio X Cell Antibody, Anti-Human CTLA-4, BN13, IgG2a, 1 MG
Supplier: Bio X Cell BE0190R001MG
The BN13 monoclonal antibody targets human CTLA-4 (CD152), a 33 kDa cell surface receptor expressed on activated T and B lymphocytes. This antibody negatively regulates cell-mediated immune responses and is utilized as an immune checkpoint blockade target for cancer treatment.
- Isotype: Mouse IgG2a, κ
- Conjugation: Unconjugated
- Immunogen: Human CTLA-4 recombinant protein
- Reported applications: In vitro CTLA-4 neutralization, Flow cytometry
- Formulation: PBS, pH 7.0; contains no stabilizers or preservatives
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Purity: ≥95%; determined by SDS-PAGE
- Sterility: 0.2 μm filtration
- Production: Purified from cell culture supernatant in an animal-free facility
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: Store at stock concentration at 4°C; do not freeze
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