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Bio X Cell Monoclonal Antibody, anti-mouse IL-4, Rat IgG1, Unconjugated, 2 1 MG
Supplier: Bio X Cell BE0199R001MG
The BVD6-24G2 monoclonal antibody reacts with mouse IL-4, a multifunctional 14 kDa cytokine primarily expressed by activated Th2 cells and NK cells. It signals through the IL-4R, stimulating B and T lymphocyte proliferation and B cell differentiation into plasma cells. This induces B cell class switching to IgE and up-regulates MHC class II production. The antibody also decreases production of Th1 cells, macrophages, IFN, and dendritic cell IL-12. Note that the BVD6-24G2 antibody does not neutralize natural or recombinant IL-4 bioactivity.
- Reacts with mouse IL-4
- Clone BVD6-24G2
- Host rat, isotype IgG1,
- Unconjugated format
- Reported applications include ELISA, ELISPOT, and flow cytometry
- Purity 95%
- Endotoxin level 1 EU/mg
- Formulated in PBS, pH 7.0 without stabilizers or preservatives
- 0.2 m filtered for sterility
- Store at 4C, do not freeze
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