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Bio X Cell Monoclonal Antibody, Clone C398.4A, Anti-ICOS (CD278), Armenian Hamster, 100 MG, 100 MG

Supplier:  Bio X Cell BE0353R100MG

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This monoclonal antibody reacts with mouse, human, rat, and monkey ICOS (inducible T cell co-stimulator), also known as CD278. ICOS is a 47-57 kDa homodimeric glycoprotein belonging to the CD28 family of costimulatory molecules, expressed on activated T cells. It co-stimulates T and B cell responses upon ICOSL binding, which is expressed on antigen-presenting cells. ICOS signaling is also important for maintaining regulatory T cell homeostasis. This antibody is commonly used to co-stimulate T cell activation and proliferation in vitro and does not block the binding of ICOS to ICOSL.

  • Clone C398.4A
  • Target antigen: ICOS (CD278)
  • Reactivity with mouse, human, rat, and monkey ICOS
  • Host species: Armenian hamster
  • Isotype: Armenian hamster IgG
  • Applications include in vitro T cell stimulation/activation, flow cytometry, and immunoprecipitation
  • Formulated in PBS, pH 7.0, without stabilizers or preservatives
  • Purity of 95%, d

Catalog No. 50-217-2877


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