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Bio X Cell InVivoMAb anti-mouse NKG2D (CD314), Clone CX5, Rat IgG1
Supplier: Bio X Cell BE0334R001MG
The CX5 monoclonal antibody reacts with mouse NKG2D, a type II transmembrane lectin-like glycoprotein also known as CD314. NKG2D is expressed on NK cells, NKT cells, CD8 T cells, γ/δ T cells, and macrophages. It has been implicated in anti-tumor surveillance, the immune response against viral infection, and in diabetes progression in NOD mice. This non-depleting antibody blocks binding of NKG2D to its ligands and mediates internalization of the receptor.
- Clone CX5
- Reacts with mouse NKG2D (CD314)
- Isotype: Rat IgG1, κ
- Immunogen: Purified mouse NKG2D
- Reported for in vivo and in vitro NKG2D blockade, and flow cytometry
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: Store at 4°C, do not freeze
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