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Bio X Cell InVivoMAb Flt-3L-Ig, Human Mouse Reactivity, 50 MG
Supplier: Bio X Cell BE0098R050MG
Flt-3L (FMS-related Tyrosine Kinase 3 Ligand) is an endogenous protein that functions as a cytokine and growth factor. Flt-3L is crucial for the development of conventional dendritic cells (cDCs) and plasmacytoid dendritic cells (pDCs). Recombinant Flt-3L-Ig is a fusion protein consisting of human Flt-3L fused to the Fc portion of human IgG1. This fusion protein is useful for activating Flt3 signaling and inducing the expansion of DC populations. Human Flt-3L-Ig is frequently reported to stimulate Flt3 signaling in vivo in mice.
- Endotoxin ≤1EU/mg (≤0.001EU/μg), determined by LAL assay
- Purity ≥95%, determined by SDS-PAGE
- Sterility 0.2 μm filtration
- Purified from cell culture supernatant in an animal-free facility
- Purification by Protein A
- Formulated in PBS, pH 7.0, contains no stabilizers or preservatives
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