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Bio X Cell Antibody, J116, PD-1, IgG1, 1 MG
Supplier: Bio X Cell BE0188R001MG
The J116 monoclonal antibody reacts with human PD-1 (CD279), a 50-55 kDa cell surface receptor that plays key roles in peripheral tolerance and the prevention of autoimmune disease. The antibody is reported to inhibit PD-1 signal transduction.
- Clone: J116
- Target: Human PD-1 (CD279)
- Isotype: Mouse IgG1, κ
- Reported applications: In vitro PD-1 neutralization, in vivo PD-1 blockade in humanized mice, in vitro Organoids/Organ-on-Chip
- Molecular weight: 150 kDa
- Purity: ≥95% (Determined by SDS-PAGE)
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Sterility: 0.2 μm filtered
- Purification: Protein G
- Formulation: PBS, pH 7.0; no stabilizers or preservatives
- Storage: Store at 4°C; do not freeze
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