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Bio X Cell Anti-Mouse 4-1BB, LOB12.3, Rat IgG1, 1 MG
Supplier: Bio X Cell BE0169R001MG
The LOB12.3 monoclonal antibody reacts with mouse 4-1BB, a TNF receptor superfamily member also known as CD137. This antibody provides costimulatory signals to T cells and NK cells, stimulating 4-1BB signaling and delaying tumor growth in vivo when combined with immune checkpoint inhibitors.
- Reacts with mouse 4-1BB (CD137)
- Clone: LOB12.3
- Isotype: Rat IgG1, κ
- Immunogen: Mouse CD137 human Fc fusion protein
- Reported applications: in vivo activation of 4-1BB
- Purity: ≥95% (SDS-PAGE)
- Endotoxin: ≤1EU/mg
- Storage: 4°C, do not freeze
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