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Bio X Cell InVivoMAb anti-CD11b, M1/70, rat IgG2b, 50 MG
Supplier: Bio X Cell BE0007R050MG
The M1/70 monoclonal antibody reacts with mouse and human CD11b, a 170 kDa membrane glycoprotein also known as integrin alpha M (ITGAM). CD11b belongs to the integrin alpha family and is primarily expressed on granulocytes and monocytes/macrophages but also expressed on dendritic cells, NK cells, and subsets of T and B cells. CD11b and CD18 combine to form Mac-1. Mac-1 functions as a complement receptor as well as a receptor for fibrinogen, factor X, and ICAM1.
- In vivo CD11b neutralization
- ILC2 cell purification
- Flow cytometry
- Purity: ≥95%, determined by SDS-PAGE
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Formulation: PBS, pH 7.0, contains no stabilizers or preservatives
- Purification: Protein G
- Sterility: 0.2 μm filtered
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