The M25 monoclonal antibody targets mouse and human IL-7, a 20-28 kDa hematopoietic growth factor. It promotes lymphoid cell differentiation, proliferation, and homeostasis, and is used for IL-7 neutralization or administration.
- Neutralizes IL-7 bioactivity; useful for cytokine administration and prolonged in vivo availability when complexed.
- Isotype: Mouse IgG2b.
- Formulation: PBS, pH 7.0; no stabilizers or preservatives.
- Endotoxin: ≤1EU/mg (≤0.001EU/μg).
- Purity: ≥95% by SDS-PAGE; 0.2 μm filtered.
- Production: Purified from animal-free cell culture via Protein G.
- Molecular weight: 150 kDa.
- Reactivities: Mouse, human.
- Clone: M25.
- Immunogen: Recombinant human IL-7.
- Storage: 4°C stock concentration; do not freeze.
- Applications: In vivo IL-7 neutralization and receptor stimulation.