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Bio X Cell Monoclonal Antibody, RM27-3E5, Mouse CD27, 100 MG
Supplier: Bio X Cell BE0348R100MG
The RM27-3E5 monoclonal antibody targets mouse CD27, a 45 kDa type I transmembrane protein of the TNF superfamily, expressed on T cells, B cells, and NK cells. Interaction with CD70 provides T-cell co-stimulation for cell proliferation and antigen-specific T-cell maintenance. Agonistic antibodies like RM27-3E5 are explored as experimental cancer treatments.
- Agonistic antibody stimulates CD27 upon binding
- Purified from animal-free facility cell culture supernatant
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Purity ≥95% (determined by SDS-PAGE)
- Endotoxin ≤1EU/mg (determined by LAL assay)
- Sterility 0.2 μm filtration
- Purification method: Protein G
- Molecular weight: 150 kDa
- Applications: in vivo/in vitro CD27 stimulation, immunoprecipitation, flow cytometry
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