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Bio X Cell anti-mouse CD80, Clone RM80, IgG2a, 25 MG
Supplier: Bio X Cell BE0365R025MG
This monoclonal antibody reacts with mouse CD80 (B7-1), a 60 kDa Ig superfamily member expressed by activated B cells, monocytes, and dendritic cells. It provides costimulatory signals for T cell activation via CD28 and inhibits T cells via CTLA-4, blocking CD80 in vivo.
- Target: mouse CD80 (B7-1)
- Host species: rat
- Isotype: rat IgG2a
- Clone: RM80
- Molecular weight: 150 kDa
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1EU/mg (≤0.001EU/µg) by LAL assay
- Purity: ≥95% by SDS-PAGE
- Sterility: 0.2 µm filtration
- Purification: protein G affinity chromatography
- Storage: store at stock concentration at 4°C; do not freeze
- Reported applications: in vivo CD80 blockade, in vitro CD80 blockade, flow cytometry
- Immunogen: mouse BCL1 cells expressing CD80
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