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Bio X Cell InVivoMAb anti-mouse TNFR2 (CD120b), Clone: TR75-54.7, 1 MG
Supplier: Bio X Cell BE0247R001MG
The TR75-54.7 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor Type II (TNFR2), also known as CD120b. It binds to TNFα or LTα ligands, influencing immunoregulation, cell proliferation, differentiation, and apoptosis. The antibody has been reported to block ligand-induced receptor signaling.
- Isotype: Armenian hamster IgG
- Immunogen: Recombinant mouse TNFR2
- Formulation: PBS, pH 7.0; contains no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg (≤0.001 EU/μg), determined by LAL assay
- Purity: ≥95%, determined by SDS-PAGE
- Sterility: 0.2 μm filtration
- Production: Purified from cell culture supernatant in an animal-free facility
- Purification: Protein G
- Molecular weight: 150 kDa
- Applications: In vivo TNFR2 blockade, in vitro TNFR2 blockade
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