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Bio X Cell InVivoMAb anti-PrP Antibody, Clone TW1, 25 MG
Supplier: Bio X Cell BE0350R025MG
The TW1 monoclonal antibody reacts with mouse and human prion protein (PrP), involved in prion neurodegenerative disorders. It binds to both PrPc and PrPSc, blocking PrP-tau interaction and ameliorating tau-related pathology in an Alzheimer's mouse model.
- Isotype: Mouse IgG2a
- Conjugation: Unconjugated
- Immunogen: Non-denatured PK-resistant PrPSc fragment from infected mouse brains
- Reported applications: In vivo PrP blocking, Western blot
- Formulation: PBS, pH 7.0; no stabilizers or preservatives
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Production: Purified from cell culture supernatant in an animal-free facility
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: Store at stock concentration at 4°C. Do not freeze.
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