MabSelect(TM) SuRe(TM) is a protein A affinity medium for capturing MAbs at process scale. MabSelect(TM) SuRe(TM) has an alkali-tolerant rProtein A ligand that allows the use of rigorous and cost-effective CIP and sanitization protocols based on 0.1 to 0.5 M NaOH. Further the ligand is protease stable leading to lower ligand leakage.MabSelect(TM) SuRe(TM) is a member of the MabSelect(TM) family of affinity chromatography media for the capture of monoclonal antibodies (MAbs) at process scale. MabSelect(TM) SuRe(TM) shares features and benefits of MabSelect(TM) such as a rigid high-flow agarose matrix that ensures excellent pressure/flow properties low non-specific binding that leads to low impurity levels in the eluate pool and an oriented ligand coupling for optimal binding capacity. In addition MabSelect(TM) SuRe(TM) features an alkali-tolerant rProtein A ligand. This ligand provides greater stability than conventional protein A-based media in the alkaline conditions used in clea