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Medchemexpress LLC Magainin 1 | 108433-99-4 | 99.9% | 2409.85 | 500 UG
Supplier: Medchemexpress LLC HYP0269500UG
Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of *Xenopus laevis*. It exhibits antibiotic activity against various Gram-negative and Gram-positive bacteria by interacting with acidic lipids to form an amphiphilic helix, leading to membrane leakage.
- Antimicrobial and amphipathic peptide
- Isolated from *Xenopus laevis* skin
- Exhibits antibiotic activity against Gram-negative and Gram-positive bacteria
- Interacts with acidic lipids through electrostatic and hydrophobic interactions
- Forms an amphiphilic helix
- Induces leakage of calcein from negatively-charged vesicles
- Binds to bovine brain phosphatidylserine sonicated vesicles
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