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Medchemexpress LLC Magainin 2 | 108433-95-0 | 98.8% | 2466.90 | 500 UG
Supplier: Medchemexpress LLC HYP0270500UG
Magainin 2, an antimicrobial peptide isolated from the skin of the African clawed frog, Xenopus laevis, exhibits antibiotic activity against numerous gram-negative and gram-positive bacteria, as well as protozoa. It exerts cytotoxicity by interacting with anionic phospholipids abundant in bacterial membranes, permeabilizing cell membranes with low toxicity to mammalian cells.
- Exhibits broad-spectrum antibiotic activity against bacteria and protozoa
- Interacts with anionic phospholipids in bacterial membranes
- Induces morphological changes in Escherichia coli
- Permeabilizes bacterial cell membranes without significant toxicity to mammalian cells
- Disrupts osmotic balance in protozoa like Paramecium caudatum
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