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Medchemexpress LLC Mal-amido-PEG12-NHS ester | 2101722-60-3 | 98.52% | C38H63N3O19 | 50 MG
Supplier: Medchemexpress LLC HY14097750MG
Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. These PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to achieve selective degradation of specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Achieves selective degradation of target proteins
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