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Medchemexpress LLC Mal-amido-PEG2-Val-Cit-PAB-PNP | 2112738-13-1 | MFCD30828687 | 98.4% | 854.86 g·mol⁻1 | C39H50N8O14 | 100 MG

Supplier: Medchemexpress LLC HY140147100MG
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2-unit PEG linker used as an intermediate in antibody-drug conjugate (ADC) synthesis. It contains a maleimide thiol-reactive handle, a PEG2 spacer, a valine-citrulline protease-cleavable dipeptide, a para-aminobenzyl self-immolative spacer, and a p-nitrophenyl activated ester for coupling.
- Cleavable Val-cit peptide for intracellular release
- Maleimide handle for thiol conjugation
- PEG2 spacer to improve hydrophilicity and reduce aggregation
- PNP-activated ester for efficient coupling to nucleophiles
- Supplied as a solid suitable for research-scale ADC assembly
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