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Medchemexpress LLC Mal-PEG2-oxyamine | 1146245-73-9 | MFCD00209801 | 95.0% | 244.24 g·mol⁻¹ | C10H16N2O5 | 5 MG
Supplier: Medchemexpress LLC HY1334545MG
Mal-PEG2-oxyamine is a PEG-based bifunctional linker used in the synthesis of proteolysis-targeting chimeras (PROTACs). It contains a maleimide group and an oxyamine moiety separated by a PEG2 spacer, enabling thiol-maleimide coupling and oxime ligation for efficient bioconjugation. The free base can be prone to instability; a TFA salt is available to improve stability.
- Bifunctional maleimide and oxyamine reactive groups.
- PEG2 spacer provides flexibility and improved solubility.
- Compatible with thiol conjugation and oxime ligation chemistries.
- Offered as a small-scale reagent (e.g., 5 mg) with reported purity around 95%.
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