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Medchemexpress LLC Mal-PEG4-propargyl | 1262681-30-0 | 99.7% | 311.33 | 50 MG
SDP

Catalog No. 5000349770
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Mal-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an Alkyne group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs are composed of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains an Alkyne group
  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Reacts with molecules possessing Azide groups
  • Facilitates protein degradation through the ubiquitin-proteasome system

Catalog No. 50-003-49770 Supplier Medchemexpress LLC Supplier No. HY14003750MG
May include imposed supplier surcharges.
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Mal-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an Alkyne group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs are composed of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains an Alkyne group
  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Reacts with molecules possessing Azide groups
  • Facilitates protein degradation through the ubiquitin-proteasome system

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