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Medchemexpress LLC Mal-PEG4-Val-Cit-PAB | 1949793-41-2 | 777.86 | C36H55N7O12 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY126672100MG

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Mal-PEG4-Val-Cit-PAB is a cleavable antibody-drug conjugate (ADC) linker containing a maleimide thiol-reactive group, a PEG4 spacer, a valine-citrulline (Val-Cit) protease-cleavable dipeptide, and a para-aminobenzyl (PAB) self-immolative spacer. It is supplied as a solid for use in synthesis of ADC drug-linkers and for conjugation to thiol-containing antibodies.

  • Maleimide thiol-reactive functional group
  • PEG4 spacer improves solubility and spacing
  • Val-Cit dipeptide cleavable by proteases such as cathepsin
  • PAB self-immolative spacer enables payload release after cleavage
  • Supplied as a solid suitable for conjugation workflows

Catalog No. 50-002-03165


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