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Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-PNP | 2112738-09-5 | 871.89 | C40H53N7O15 | 5 MG
SDP

Catalog No. 5000202624
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Mal-PEG4-Val-Cit-PAB-PNP is a protease-cleavable, four-unit polyethylene glycol (PEG4) ADC linker containing a maleimide reactive group and a Val-Cit-PAB cleavable spacer. It is used in the synthesis of antibody-drug conjugates to provide protease-sensitive release of payloads.

  • Protease-cleavable PEG4 linker useful for ADC synthesis.
  • Maleimide reactive group enables thiol conjugation to antibodies.
  • Val-Cit-PAB spacer provides protease-sensitive payload release.
  • Soluble in DMSO (125 mg/mL) and formulatable for in vivo use (solubility ≥ 2.08 mg/mL with recommended solvent systems).
  • Storage: protect from light; in solvent -80°C for 6 months, -20°C for 1 month.
  • For research use only; not fully validated for medical applications.

Catalog No. 50-002-02624 Supplier Medchemexpress LLC Supplier No. HY1401455MG
May include imposed supplier surcharges.
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Mal-PEG4-Val-Cit-PAB-PNP is a protease-cleavable, four-unit polyethylene glycol (PEG4) ADC linker containing a maleimide reactive group and a Val-Cit-PAB cleavable spacer. It is used in the synthesis of antibody-drug conjugates to provide protease-sensitive release of payloads.

  • Protease-cleavable PEG4 linker useful for ADC synthesis.
  • Maleimide reactive group enables thiol conjugation to antibodies.
  • Val-Cit-PAB spacer provides protease-sensitive payload release.
  • Soluble in DMSO (125 mg/mL) and formulatable for in vivo use (solubility ≥ 2.08 mg/mL with recommended solvent systems).
  • Storage: protect from light; in solvent -80°C for 6 months, -20°C for 1 month.
  • For research use only; not fully validated for medical applications.

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