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Cayman Chemical Malabaricone B, Purity: ≥98%, CAS: 63335-24-0, 10 mg
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Catalog No. 502989722
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A diarylnonanoid with diverse biological activities; an inhibitor of sphingomyelin synthase 1 and -2 (IC50s = 3.5 and 2.5 µM, respectively); active against S. aureus, B. subtilis, and S. durans (MIC = 1 µg/ml for all) and three strains of C. albicans (MICs = 4-16 µg/ml); cytotoxic to A549, A375, Jurkat, A431, U937, and MCF-7 cells (IC50s = 8.1, 26.7, 27.4, 9.5, 27.5, and 9.3 µM, respectively) but not non-cancerous cells; increases the levels of ROS and induces apoptosis in A549 cells; reduces TBARS formation by 28.2% in rat liver mitochondria at 2 µg/ml; reduces stomach ulceration in a mouse model of indomethacin-induced gastric ulcer at 10, 15, and 20 mg/kg

Catalog No. 50-298-9722 Supplier Cayman Chemical Supplier No. 2991110 MG
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A diarylnonanoid with diverse biological activities; an inhibitor of sphingomyelin synthase 1 and -2 (IC50s = 3.5 and 2.5 µM, respectively); active against S. aureus, B. subtilis, and S. durans (MIC = 1 µg/ml for all) and three strains of C. albicans (MICs = 4-16 µg/ml); cytotoxic to A549, A375, Jurkat, A431, U937, and MCF-7 cells (IC50s = 8.1, 26.7, 27.4, 9.5, 27.5, and 9.3 µM, respectively) but not non-cancerous cells; increases the levels of ROS and induces apoptosis in A549 cells; reduces TBARS formation by 28.2% in rat liver mitochondria at 2 µg/ml; reduces stomach ulceration in a mouse model of indomethacin-induced gastric ulcer at 10, 15, and 20 mg/kg

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