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Medchemexpress LLC Maleimide | 541-59-3 | 97.07 | 1 G
Supplier: Medchemexpress LLC HYW0073241G
Maleimide is a chemical compound primarily used in cancer research for the production of antibody-drug conjugates (ADC). It also finds application in preparing fluorogenic probes for the specific detection of thiol analytes. This compound is known for its ability to bind rapidly and covalently to the sulfhydryl (-SH) group of cysteine residues, a characteristic that can be leveraged in drug delivery systems to enhance cell uptake efficiency.
- Used for production of antibody-drug conjugate (ADC) in cancer research.
- Leveraged for preparation of fluorogenic probes for specific detection of thiol analytes.
- Binds rapidly and covalently to sulfhydryl (-SH) group of cysteine residues.
- Can be used in drug delivery systems for improved cell uptake efficiency.
- Maleimide modified liposomes exhibit antitumor effects in mouse models.
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