Malononitrile, 99%

Description

CAS: 109-77-3 | C3H2N2 | 66.063 g/mol

Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Crosslinking agent for modification of proteins via amidationMalononitrile is used as a precursor in the preparation of anti-cancer drug, triamterene, adenine, methotrexate, thiamine, acrylic fibers and dyes. It is used in Knoevenagel condensation to prepare 2-chlorobenzalmalononitrile by reacting with 2-chlorobenzaldehyde. It acts as a leaching agent for gold. It is used as a raw material for the Gewald reaction of ketone or aldehyde to produce 2-aminothiophene using elemental sulfur and a base. Further, it plays an important role in the preparation of [1,6]-naphthyridines, gamma-ketoamides, 1,4-dihydropyridine, chromeno[2,3-b]pyridine and dihydro-1,4-dithiepine frameworks.

Solubility
Soluble in water, acetone, acetic acid, chloroform, ethanol, ether and benzene.

Notes
Store in a cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids and strong bases.

Specifications

Chemical Identifiers

• CAS: 109-77-3
• Molecular Formula: C3H2N2
• MDL Number: MFCD00001883
• InChI Key: CUONGYYJJVDODC-UHFFFAOYSA-N
• Synonym: malononitrile, dicyanomethane, cyanoacetonitrile, malonic dinitrile, methylene cyanide, dicyanmethane, malonodinitrile, malonic acid dinitrile, methylenedinitrile, methane, dicyano
• PubChem CID: 8010
• ChEBI: CHEBI:33186
• IUPAC Name: propanedinitrile

• Melting Point: 30°C to 34°C
• Density: 1.049
• Boiling Point: 220°C to 222°C
• Flash Point: 112°C (233°F)
• Refractive Index: 1.415
• Quantity: 100 g
• UN Number: UN2647
• Beilstein: 773697
• Merck Index: 14,5711
• Solubility Information: Soluble in water,acetone,acetic acid,chloroform,ethanol,ether and benzene.
• SMILES: C(C#N)C#N
• Molecular Weight (g/mol): 66.063
• Formula Weight: 66.06
• Percent Purity: 99%
• Chemical Name or Material: Malononitrile

Safety and Handling

Hazard Category	H301+H311+H331
Hazard Statement	GHS H Statement H301-H311-H331 Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: MALONONITRILE
EINECSNumber	203-703-2
RTECSNumber	OO3150000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only