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Medchemexpress LLC Malotilate | 59937-28-9 | 99.5% | C12H16O4S2 | 100 MG
Supplier: Medchemexpress LLC HYA0060100MG
Malotilate is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM. It prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes. For research use only.
- Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
- Stimulates 12- and 15-lipoxygenase pathways
- Prevents acute experimental liver injury induced by various hepatotoxic compounds
- Normalizes lowered serum cholesterol in rats with hypocholesterolemia
- Normalizes inhibition of triglyceride secretion from livers in rats with CCl4-induced liver damage
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