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Medchemexpress LLC Malotilate (NKK 105) | 59937-28-9 | 99.5% | C12H16O4S2 | 1 ML
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Supplier:  Medchemexpress LLC HYA006010MM/1ML

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Malotilate (NKK 105) is an orally active hepatotropic agent and an anti-fibrotic substance. It selectively inhibits 5-lipoxygenase (5-LOX) with an IC50 of 4.7 μM, preventing hepatocytic injury in alcohol-pyrazole hepatitis and reducing hepatic acetaldehyde levels.

  • Prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis
  • Decreases hepatic acetaldehyde levels
  • Prevents the retention of transferrin in the hepatocytes
  • Reduces collagen synthesis and cell migration activity of fibroblasts in vitro
  • Demonstrated to prevent acute experimental liver injury induced by various hepatotoxic compounds

Catalog No. 50-004-32034


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