Invitrogen™ Human MAP4K5 (KHS1), GST Tag Recombinant Protein

Catalog No.	Quantity
PV3682	10 μg

Catalog No. PV3682 Supplier Invitrogen™ Supplier No. PV3682

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAP4K5 (KHS1) is a serine/threonine kinase that belongs to the GCK family of kinases and has been implicated as an upstream regulator of MAP kinase signaling pathways. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for MAP4K5.

Specifications

• Accession Number: Q9Y4K4
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 2mM DTT, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 11183
• Molecular Weight (g/mol): 122.5 kDa
• Name: Human MAP4K5 (KHS1), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 4432415E19Rik; fl74c10; GCKR; germinal center kinase-related; KHS; KHS1; Kinase homologous to SPS1/STE20; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 5; map4k5; MAPK/ERK kinase kinase kinase 5; MAPKKKK5; MEK kinase kinase 5; MEKKK 5; mitogen-activated protein kinase kinase kinase kinase 5; RGD1562028; wu:fl74c10; zgc:55719; zgc:55985
• Common Name: MAP4K5
• Gene Symbol: Map4k5
• Kinase Family: STE20 Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
• Kinase Group: Ser⁄Thr Kinases: STE Group
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
• Target Entry: MAP4K5
• Target Gene: mitogen-activated protein kinase kinase kinase kinase 5
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction
• Purity or Quality Grade: 80% by SDS-PAGE