Invitrogen™ Human MAPKAPK2 (Inactive), His Tag Recombinant Protein

Catalog No.	Quantity
PV3316	100 μg

Catalog No. PV3316 Supplier Invitrogen™ Supplier No. PV3316

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length, Recombinant, Inactive.

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.

Specifications

• Accession Number: P49137
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 0.05mM EDTA, 150mM NaCl, 2mM DTT, 0.05% Triton X-100, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 9261
• Molecular Weight (g/mol): 48.8 kDa
• Name: Human MAPKAPK2 (Inactive), His Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
• Common Name: MAPKAPK2
• Gene Symbol: MAPKAPK2
• Kinase Family: MAPKAPK Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.05mM EDTA, 0.05% Triton X-100, 2mM DTT, 50% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Kinase Group: Ser⁄Thr Kinases: CAMK Group
• Shipping Condition: Dry Ice
• Target Gene: mitogen-activated protein kinase-activated protein kinase 2
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Full Length, Recombinant, Inactive
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Signal Transduction
• Purity or Quality Grade: 95% by SDS-PAGE