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Apexbio Technology LLC Maprotiline HCl 10347-81-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B13385.1
Maprotiline HCl (CAS 10347-81-6) is an orally administered selective norepinephrine reuptake inhibitor primarily investigated for its antidepressant properties Mechanistically Maprotiline modulates the extracellular signal-regulated kinase (ERK) pathway and interacts with cellular retinoic acid binding protein 1 (CRABP1) promoting apoptotic processes in cancer cells In preclinical studies Maprotiline has demonstrated the ability to induce cell death via these signaling mechanisms Additionally due to its effects on neuropathic pain modulation Maprotiline is utilized in research exploring chronic pain pathways and investigating pharmacological interventions for pain management
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