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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | MFCD00078833 | >99.9% | 50 MG
Supplier: Medchemexpress LLC HYB0444R50MG
Maprotiline hydrochloride is an analytical standard and a highly selective noradrenergic reuptake inhibitor. It exhibits strong antidepressant, antitumor, and neuropathic pain-relieving effects. This compound induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1, making it a valuable subject for research in various therapeutic areas.
- Inhibits the growth of Huh7 and HepG2 cells and induces cell apoptosis.
- Inhibits the metastasis of liver cancer cells.
- Targets CRABP1 and regulates cholesterol biosynthesis in HCC cells.
- Restrains HCC cell migration with inhibition of epithelial-mesenchymal transition.
- Inhibits liver cancer tumor growth in mice.
- Effectively reduces neuropathic pain in mice.
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