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Cayman Chemical MaprotIlInhydrochlorIde 50mg
SDP

Supplier:  Cayman Chemical 1589250 MG

Encompass_Preferred

A tricyclic antidepressant; binds to NET (Kd = 11 nM); selective for NET over the serotonin and dopamine transporters (Kds = 5,800 and 1,000 nM, respectively); binds to 5-HT2A (Ki = 51 nM), as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors (Kds = 2, 570, 90, and 350 nM, respectively); inhibits norepinephrine reuptake in rat brain and peripheral tissues; reduces isolation-induced aggressive behavior and inhibits electrical foot-shock stimulation-induced belligerence in mice from 3-10 mg/kg; prevents acid sphingomyelinase activation and subsequent ceramide release induced by pp-VSV-SARS-CoV-2 infection in Vero cells at 20 µM

Catalog No. 50-297-2152


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