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Medchemexpress LLC Mardepodect hydrochloride | 2070014-78-5 | 99.9% | C25H21ClN4O | 100 MG
Supplier: Medchemexpress LLC HY50098A100MG
Mardepodect hydrochloride is a potent, orally active, and selective PDE10A inhibitor with an IC50 of 0.37 nM. It demonstrates over 1000-fold selectivity compared to other PDEs and is capable of crossing the blood-brain barrier.
- Potent and orally active
- Selective PDE10A inhibitor
- IC50 of 0.37 nM
- Over 1000-fold selectivity over other PDEs
- Crosses the blood-brain barrier
- Active in conditioned avoidance response assay (CAR) with an ED50 of 1 mg/kg
- Increases striatal cGMP dose-dependently in mice
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