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Medchemexpress LLC Mardepodect hydrochloride | 2070014-78-5 | 99.9% | C25H21ClN4O | 25 MG
Supplier: Medchemexpress LLC 25MGHY50098A
Mardepodect hydrochloride is a potent, orally active, and selective PDE10A inhibitor with an IC50 of 0.37 nM, demonstrating over 1000-fold selectivity compared to other PDEs. It is capable of crossing the blood-brain barrier.
- Potent, orally active, and selective PDE10A inhibitor
- IC50 of 0.37 nM
- Exhibits >1000-fold selectivity over other PDEs
- Can cross the blood-brain barrier
- Active in the conditioned avoidance response (CAR) assay with an ED50 of 1 mg/kg
- Induces a dose-dependent increase in striatal cGMP in mice
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