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Cayman Chemical MavorIxafor 10mg
SDP

Supplier:  Cayman Chemical 2843910 MG

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A CXCR4 antagonist (IC50 = 13 nM in a radioligand binding assay); selective for CXCR4 over CCR1, CCR2b, CCR4, CCR5, CXCR1, and CXCR2 (IC50s = >10 µM for all); reduces CXCL12-induced chemotaxis of CCRF-CEM T cells (IC50 = 19 nM); inhibits fusion of CHO-K1 cells expressing gp120 to P4 MAGI cells IC50 = 1.5 nM; decreases HIV-1 NL4.3 viral replication in MT-4 cells and isolated human PBMCs (IC50s = 2 and 9 nM, respectively)

Catalog No. 50-294-0331


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