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Medchemexpress LLC Max-40279 hemifumarate | 2388506-43-0 | 99.6% | 554.59 | C22H23FN6OS·1/2C4H4O4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY145723B5MG

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MAX-40279 hemifumarate is a dual, orally active small-molecule inhibitor of FLT3 and FGFR kinases, with activity against FLT3 mutants such as FLT3D835Y. It reduces NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition, making it suitable for preclinical acute myelogenous leukemia research.

  • Dual FLT3 and FGFR kinase inhibition.
  • Orally active small-molecule profile.
  • Retains activity against FLT3 mutants such as D835Y.
  • Reduces NDRG1 phosphorylation at Ser330.
  • Suppresses endothelial-to-mesenchymal transition (EndMT).
  • High reported purity (99.6%).
  • Available in small research quantities for preclinical studies.

Catalog No. 50-002-21576


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