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Medchemexpress LLC MAX-40279 hemifumarate | 2388506-43-0 | 99.6% | C22H23FN6OS·1/2C4H4O4 | 10MG
Supplier: Medchemexpress LLC HY145723B10MG
MAX-40279 hemifumarate is a small-molecule research inhibitor that targets FLT3 and FGFR kinases. It is orally active and retains activity against clinically relevant FLT3 mutants (for example, D835Y), making it suitable for studies of kinase inhibitor resistance and acute myelogenous leukemia (AML) signaling. It also inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT).
- Dual FLT3 and FGFR kinase inhibition
- Orally active and effective against FLT3 mutants such as D835Y
- Useful for AML research and studies of inhibitor resistance
- Inhibits NDRG1 phosphorylation at Ser330 and suppresses EndMT
- High purity (~99.6%) and fully characterized chemical properties
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