Medchemexpress LLC Mbm-55 | 2083622-09-5 | 99.5% | 498.55 | C28H27FN6O2 | 50 MG

Supplier:  Medchemexpress LLC HY10102950MG

MBM-55 is a small-molecule research inhibitor of NIMA-related kinase 2 (Nek2) with low-nanomolar potency. It inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis, and has demonstrated antitumor activity in mouse models with no obvious toxicity reported. The compound is supplied for laboratory research in solid form and as DMSO solution.

• Potent Nek2 inhibition (IC50 ~1 nM).
• Selectivity profile with limited off-target activity against RSK1 and DYRK1a.
• Induces cell cycle arrest and apoptosis in cancer cells.
• Demonstrated antitumor activity in mouse models without obvious toxicity.
• Available as a solid and as a DMSO solution in multiple pack sizes.
• High purity (≈99.5%) and molecular weight 498.55.

Catalog No. 50-002-13364