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ATCC MC3T3-E1 Subclone 4; Preosteoblast; Mouse (Mus musculus)
Supplier: ATCC CRL2593
MC3T3-E1 Subclone 4 preosteoblasts were isolated from the cloned but phenotypically heterogeneous MC3T3-E1 cell line. This subclone was selected for high osteoblast differentiation and mineralization after growth in medium containing ascorbic acid. This cell line is a good model for studying in vitro osteoblast differentiation, particularly ECM signaling. It's behavior is similar to primary calvarial osteoblasts.
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