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CPC Scientific MCA-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(DNP)-Arg-Arg-NH2 (trifluoroacetate salt) 1MG
SDP

Supplier:  CPC Scientific AMYD110B

Encompass

Fluorescent peptide substrate that contains the wild-type amyloid precursor protein (APP) beta-secretase cleavage site. It is used for assaying beta-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). Studies reveal that TOP is a potential beta-secretase candidate and is involved in the processing of APP in vivo. ONE-LETTER SEQUENCE: Mca-SEVKMDAEFR-K(DNP)-RR-NH2MOLECULAR FORMULA: C87H129N27O28S1MOLECULAR WEIGHT:2033.2STORAGE CONDITIONS: -20 5CRESEARCH AREA: Alzheimer's DiseaseREFERENCES: H. Koike et al., J. Biochem., 126, 235 (1999)

Catalog No. 50-210-8737


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