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Bachem Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
SDP

Supplier:  Bachem 4028885.0005

Encompass_Preferred

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Trifluoroacetate, 720710-69-0, C55H80N16O16, Mr 1221.34, 5mg. The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH2 with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to Mca-PLGL-Dpa-AR-NH2, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH2 for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.

Catalog No. 50-260-486


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