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Medchemexpress LLC MCC950 | 210826-40-7 | 99.8% | 200 MG

Supplier: Medchemexpress LLC HY12815200MG
MCC950 is a potent and selective NLRP3 inhibitor, with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs. It blocks canonical and non-canonical NLRP3 activation at nanomolar concentrations. This product is for research use only.
- Potent and selective NLRP3 inhibitor
- Blocks canonical and non-canonical NLRP3 activation
- Specifically inhibits NLRP3, not AIM2, NLRC4, or NLRP1
- Reduces interleukin-1β (IL-1β) production
- Attenuates the severity of experimental autoimmune encephalomyelitis (EAE)
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