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Medchemexpress LLC MCC950 | 210826-40-7 | 99.8% | 200 MG
SDP

Supplier:  Medchemexpress LLC HY12815200MG

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MCC950 is a potent and selective NLRP3 inhibitor, with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs. It blocks canonical and non-canonical NLRP3 activation at nanomolar concentrations. This product is for research use only.

  • Potent and selective NLRP3 inhibitor
  • Blocks canonical and non-canonical NLRP3 activation
  • Specifically inhibits NLRP3, not AIM2, NLRC4, or NLRP1
  • Reduces interleukin-1β (IL-1β) production
  • Attenuates the severity of experimental autoimmune encephalomyelitis (EAE)

Catalog No. 50-003-42336


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