Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC MCC950 sodium(Synonyms: CP-456773 sodium, CRID3 sodium, MCC-950 sodium, MCC950 sodium salt), 200mg, CAS: 256373-96-3.
Supplier: Apexbio Technology LLC B7946200
MCC950 sodium (CAS 256373-96-3) is a selective small-molecule inhibitor targeting the NOD-like receptor family protein 3 (NLRP3) inflammasome MCC950 sodium inhibits NLRP3 activation in murine bone marrow-derived macrophages (BMDMs) with an IC50 of 7 5 nM and demonstrates comparable selectivity and potency in human monocyte-derived macrophages (HMDMs) It specifically blocks both canonical and noncanonical activation pathways without affecting other inflammasomes such as AIM2 NLRC4 and NLRP1 Due to its selectivity MCC950 sodium is valuable in investigating NLRP3-associated inflammatory and autoimmune conditions
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?