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Cayman Chemical mCherry mRNACap-15mCTPψ 1mg
SDP

Supplier:  Cayman Chemical 397991 MG

Encompass_Preferred

An inhibitor of the SOS1-K-RasG12C protein-protein interaction (Ki 1.9 nM) selective for the SOS1-K-RasG12C protein-protein interaction over the SOS1-K-Ras protein-protein interaction (IC50 10000 nM) decreases phosphorylated ERK levels in MNK1 cancer cells (IC50 29 nM) reduces tumor volume and phosphorylated ERK levels when combined with MTX-849 in a PaCa-2 pancreatic cancer mouse xenograft model at 25 or 50 mg/kg twice per day

Catalog No. 50-294-2225


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