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Cayman Chemical MCL0020trIfluoROCTAte sal 10mg
Supplier: Cayman Chemical 4154410 MG
An MC4R antagonist; selectively inhibits [Nle4,D-Phe7]-α-MSH binding to recombinant human MC4R over MC1R and MC3R (IC50s = 11.63, >10,000, and 1,115 nM, respectively); inhibits α-MSH-induced cAMP production in COS-1 cells expressing human MC4R from 0.1-100 µM; reduces stress-induced decreases in the time spent in the light area of the light/dark exploration test in mice; reverses restraint stress-induced decreases in food intake in rats
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