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Medchemexpress LLC MDEG-541 | C₃₅H₃₈N₄O₆S₂ | 50 MG
SDP

Supplier:  Medchemexpress LLC HY15025950MG

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MDEG-541 is a potent MYC-MAX degrader. It is a PROTAC based on the MYC-MAX dimerization inhibitor 10058-F4 derivative 28RH and Thalidomide. It demonstrates antiproliferative activity and reduces the expression of GSPT1, MYC, GSPT2, and PLK1 proteins.

  • Decreases the expression of GSPT1, MYC, GSPT2, and PLK1 proteins in a time-dependent manner in KP4 cells.
  • Inhibits cell viability in HCT116 and PSN1 cells.
  • Reduces MYC expression in a dose-dependent manner in HCT116 and PSN1 cells.

Catalog No. 50-003-75579


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